A stylized hero image of a doctor and her patient reviewing a document. There is a bending, thick teal line spanning the full horizontal space in the background.

Now enrolling

A clear path for PCED starts here

ABOUT PCED

If you’re experiencing persistent, unexplained eye pain, swelling of the eye, sensitivity to light, pain with blinking, or painful eye movements, you may have persistent corneal epithelial defect, or PCED.

This rare condition occurs when the outer layer of the cornea fails to heal within a normal, 10- to 14-day timeframe, despite standard treatments. PCED is often caused by underlying conditions like Sjögren’s syndrome and neurotrophic keratitis. It can also occur after eye trauma. Only a healthcare professional can properly diagnose PCED.

Individuals with any of the symptoms listed above, or with a diagnosed eye wound that has been unresponsive to standard treatment for at least 2 weeks, may be eligible for a new clinical trial.

ABOUT THE TRIAL

This study is evaluating the safety and efficacy of a once-weekly topical gel treatment for children and adults aged 2 years and older with PCED. This is a unique opportunity for people with PCED to help advance medical research.

The study is actively enrolling participants for once-weekly treatment and includes:

A screening period
A treatment period (up to 8 weeks)
A follow-up period (4 weeks)
An open-label treatment period (up to 8 weeks)

Potential side effects previously reported may include eye pain, headache, corneal epithelium defect, white or yellow discharge at the corners of the eyes, and/or an ocular condition called symblepharon.

YOU MAY BE ELIGIBLE

Your responses to the survey indicate that you may be eligible to participate in this study. If you would like to receive further information, please provide the contact information requested below.

Please note: Financial assistance is available for patients who need to travel or spend the night away from home to participate in the trial.

Once you select your preferred site, please save its phone number and address for your records.

Please enter a zip code to view results

Trial Submit Form

The form on step 2 of the patient site homepage process.

"*" indicates required fields

Instagram

This field is for validation purposes and should be left unchanged.

Potential study participant’s first name*

Month*

Day*

Year*

Your first name (if submitting on behalf of another person)

Your last name (if submitting on behalf of another person)

Email address*

Phone number*

Select best time to contact you:

The information you provide will be used for the purpose of evaluating eligibility for the clinical study and may be reviewed by the study sponsor, its research partners, or clinical trial sites involved in conducting the study. Your responses will be handled in accordance with applicable privacy laws and the study sponsor’s Privacy Policy.

By selecting “Submit” and continuing, you confirm that:

You have read and understand the information provided and are voluntarily providing your personal information
If you are submitting this form on the behalf of someone else, you confirm you are the parent or authorized legal representative of the individual whose information is being provided, and that you have the legal authority to disclose the provided personal and health information
You agree that your information can be shared with the selected clinical trial site, and that you can be contacted by phone and/or email by a member of the research team or the clinical trial site with additional information about the clinical trial, including risks, benefits, and participation requirements
You understand that completing the survey does not guarantee enrollment in a clinical trial

THANK YOU!

We appreciate you taking the time to complete this survey. A member from the trial team at the study site you selected will contact you.

If you have questions in the meantime, please do not hesitate to reach out to the site you selected with the phone number or email address provided.

THANK YOU FOR YOUR INTEREST

We appreciate you taking the time to complete this survey. Unfortunately, based on your answers to the survey, you are not eligible for the trial at this time. The information you submitted will not be saved. Please consult with your physician or other qualified healthcare professional for evaluation, diagnosis, and treatment.

Learn more about PCED.

Trial form unavailable

Please enable JavaScript in your browser to enable the trial form.